Worse Prostate Cancer Outcomes With 5-Alpha-Reductase Inhibitors

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96. Background: To investigate the impact of 5-alpha-reductase inhibitors (5-ARIs) usage on radiotherapy outcomes for localized prostate cancer.Methods: From our institutional database of over 2500 patients, we identified 203 patients on a 5-ARI. They were all treated with either external beam radiotherapy (EBRT) or brachytherapy for localized prostate cancer.

A recent study found prior use of 5-alpha-reductase inhibitors for benign prostatic hyperplasia was associated with delayed prostate cancer diagnosis and worse prostate cancer. Men using 5 945;-reductase inhibitors were diagnosed with prostate cancer 3.6 years after having increased levels of prostate-specific antigen .

worse prostate cancer outcomes With 5-Alpha-Reductase Inhibitors Treatment with 5-alpha-reductase inhibitors (5-ARIs) is associated with shorter time to diagnosis and worse mortality in prostate.

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Men receiving a 5-alpha reductase inhibitor (5-ARI) for treatment of benign prostatic hypertrophy who developed prostate cancer were more likely to have a delay in diagnosis as well as worse.

A new study found that "prior use of 5-alpha-reductase inhibitors for benign prostatic hyperplasia (BPH) was associated with delayed prostate cancer diagnosis and worse prostate cancer outcomes." Find out what this means for prostate cancer patients.

5-Alpha Reductase Inhibitors for Treatment of benign prostatic hyperplasia:. outcomes studied included need for prostate-related surgery, acute urinary.. cancer. The targeted population was adult males with benign prostatic.. various outcomes to assess worst-case scenarios where all patients lost.

Aquablation Shows "Promising" Outcomes in BPH Patients With Large Prostates; Worse Prostate Cancer Outcomes With 5-Alpha-Reductase Inhibitors; Enucleation Might Be Better Option for Men With Benign Prostatic Hyperplasia

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5-alpha reductase inhibitors interfere with the effect of certain male hormones (androgens) on the prostate. This slows the growth of the prostate and can even cause it to become smaller, which may help improve the symptoms of benign prostatic hyperplasia (BPH) .

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This article reviews the current status of therapy with 5-reductase inhibitors. the use of 5ARIs for prostate cancer chemoprevention in patients receiving 5ARIs for.. whereas both parameters worsened again during tamsulosin treatment after. with the dual 5alpha-reductase inhibitor dutasteride: results of 4-year studies.